FIELD: organic chemistry. SUBSTANCE: product - methyl - 2,4,6 - tri - O - acetyl - 3 - deoxy - 3,3 - C - dicyano - a - D - glucopyranoside, gross- formula is C15H18O8N2, m. p. is 118-119 C. Reagent 1: methyl - 2,4,6 - tri - O - acetyl - 3 - deoxy - 3 - C - carbamoyl - 3 - C - cyano - LD50 - D - glucopyranoside. Reagent 2: thionyl chloride. Reaction conditions: in the presence of dimethylformamide, at 60 C for 1 h. Value α = 197 mg/kg. After a single administration of synthesized substance inhibition of growth of leukosis tumor P-388, melanoma B-16 and Lewis lung carcinoma is observed (by 75; 88 and 82% , respectively). Synthesized compound can be used in medicine. EFFECT: high antitumor activity of the end product. 1 tbl
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机译：领域：有机化学。物质：产物-甲基-2,4,6-三-O-乙酰基-3-脱氧-3,3-C-双氰基-a-D-吡喃葡萄糖苷，总式为C 15 H 18 O 8 N 2 ，m。 p。是118-119℃。试剂1：甲基-2,4,6-三-O-乙酰基-3-脱氧-3-C-氨基甲酰基-3-C-氰基-LD 50 -D -吡喃葡萄糖苷。试剂2：亚硫酰氯。反应条件：在二甲基甲酰胺存在下，在60℃下反应1小时。值α= 197 mg / kg。单次施用合成物质后，抑制了白血病P-388的生长，观察到黑色素瘤B-16和Lewis肺癌（分别为75％，88％和82％）。合成的化合物可用于医学。效果：最终产品具有很高的抗肿瘤活性。 1汤匙
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