Inhibition of the in vitro infectivity and the cytopathic effect of HTLV-III / LAV by 2'3'-dideoxyinosine, 2'3'-dideoxyguanosine or 2'3'-dideoxyadenosine.

摘要

The present invention relates to a method of alleviating the cytopathic effects of HTLV-III virus on cells which comprises contacting the virus with an effective amount of a purine base, which is 2 min ,3 min -dideoxyinosine, 2 min ,3 min -dideoxyguanosine, 2 min ,3 min -dideoxyadenosine or phosphates thereof.