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recombinant human unglycosiliertes 2 in a reduced form, manufacturing process and medical application.

机译:重组人解糖寡糖2的简化形式,制造工艺和医学应用。

摘要

The invention relates to a nonglycosylated, recombinant human IL2 in which the three cysteines in positions 58, 105 and 125 are in the reduced form and which exhibits a biological activity comparable with that of the oxidised IL2 having the same sequence and containing a disulphide bridge in position 58-105, to the process for obtaining it and to its application as a medication.
机译:本发明涉及一种非糖基化的重组人IL2,其中58、105和125位的三个半胱氨酸处于还原形式,并且其生物学活性与具有相同序列并在其中含有二硫键的氧化IL2相当。位置58-105,涉及获得它的方法及其作为药物的用途。

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