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Autoimmunity Characteristic intestinal diseased remedy medicine

机译:自身免疫性肠病特色药物

摘要

PURPOSE:To obtain the title remedy by combining steroid with a trypsin inhibitor. CONSTITUTION:A remedy for autoimmune intestinal diseases is obtained by a combination of a steroid (a steroid with anti-inflammatory activity or its derivative) with a trypsin inhibtor such as urine-originating trypsin inhibtor or aprotinin. The preparation is effective against ulcerative colities, regional ileitis and intestinal Behchet's diseases. The steroid is used in the form of a water-soluble steroid (an organic acid salt with prednisolone), a lipid emulsion containing steroid, liposome containing steroid or a rectal preparation containing steroid. The administration is suitably effected orally or parenterally in combination once to several times a day. The dose is 0.1-10mg/day of the steroid and 1-100,000units/day of the trypsin inhibitor.
机译:目的:通过类固醇与胰蛋白酶抑制剂的结合来获得标题的补救措施。组成:一种针对自身免疫性肠道疾病的治疗方法是将类固醇(具有抗炎活性的类固醇或其衍生物)与胰蛋白酶抑制剂(例如尿液胰蛋白酶抑制剂或抑肽酶)联合使用。该制剂对溃疡性结肠炎,局部性回肠炎和肠白塞氏病有效。类固醇以水溶性类固醇(与泼尼松龙的有机酸盐),包含类固醇的脂质乳剂,包含类固醇的脂质体或包含类固醇的直肠制剂的形式使用。每天一次或多次口服或胃肠外给药适当地进行给药。剂量为类固醇0.1-10mg /天,胰蛋白酶抑制剂1-10万单位/天。

著录项

  • 公开/公告号JPH0774160B2

    专利类型

  • 公开/公告日1995-08-09

    原文格式PDF

  • 申请/专利权人 株式会社ミドリ十字;八木田 旭邦;

    申请/专利号JP19870052188

  • 发明设计人 八木田 旭邦;

    申请日1987-03-09

  • 分类号A61K38/55;A61K31/56;

  • 国家 JP

  • 入库时间 2022-08-22 04:29:22

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