Manufacturing method null of azorirumechirushikuroarukanoru

摘要

PURPOSE:To readily obtain the subject substance useful as fungicide for agricultural and horticulture, etc., in high yield, by reacting cycloalkanone derivatives with sulfonium ylide, etc., and alkali metal salt of azole compound, etc., in a solvent such as DMSO. CONSTITUTION:A compound expressed by formula I (R1 is H or 1-5C alkyl; R2 is H or 1-2C alkyl; X is halogen, alkyl, phenyl or CN, etc.; m is 1-5; n is 0-2) and a compound expressed by formula II (A is N or CH; M is alkali metal or H) are dissolved in a polar solvent having amide bonding, DMSO or mixed solvent of said solvent and 1-5C alcohol, then trimethylsufonium halide or trimethylsulfoxonium halide and a base are intermittently added and reacted at 70-110 deg.C for 5-10 hour to obtain a compound expressed by formula III. Said method is carried out in one stage and simple, thus slight by-product is generated.