首页> 外国专利> INDOLE DERIVATIVES, PROCESS OF THEIR PREPARATION, INTERMEDIATES OF SUCH PROCESS, PHARMACEUTICAL PREPARATIONS CONTAINING SAID INDOLE DERIVATIVES AND THEIR USE

INDOLE DERIVATIVES, PROCESS OF THEIR PREPARATION, INTERMEDIATES OF SUCH PROCESS, PHARMACEUTICAL PREPARATIONS CONTAINING SAID INDOLE DERIVATIVES AND THEIR USE

机译:吲哚衍生物,其制备过程,该过程的中间体,包含所述吲哚衍生物的药物制剂及其用途

摘要

indolovu00e9 derivatives of general formula i, in which the mean residues (a) or (b); r.sub.1.n.represents the residues (c), (d), (e) or (f), and their pharmaceutically acceptable salts are suitable psychotherapeutika taking effective serotoninovu00fdmi (5 - ht.sub.1.n.) agonists and may be used for the treatment of depression, anxiety disorders, eating habits, obesity, drug abuse, the histamine cefalalgie, migraines,pain and chronic paroxysmal hemikranie and headaches associated with other disorders and taken disorders resulting from the deficit serotonergic neurotransmission.these compounds may also be used as a centrally acting antihypertenzu00edva and vasodilators. described is also a method of preparation of such compounds and intermediate products of this process. and
机译:通式i的吲哚洛夫衍生物,其中平均残基(a)或(b); r.sub.1.n.代表残基(c),(d),(e)或(f),它们的药学上可接受的盐是服用有效serotoninov u00fdmi(5-ht.sub.1.n 。)激动剂,可用于治疗抑郁症,焦虑症,饮食习惯,肥胖症,药物滥用,组胺头孢类,偏头痛,疼痛和慢性阵发性偏头痛以及与其他疾病相关的头痛,以及由于血清素能神经传递不足而引起的疾病这些化合物也可用作中枢作用的降血压药和血管扩张药。还描述了该方法的此类化合物和中间产物的制备方法。 r和

著录项

  • 公开/公告号CZ9401280A3

    专利类型

  • 公开/公告日1995-02-15

    原文格式PDF

  • 申请/专利权人 PFIZER INC.;

    申请/专利号CZ19940001280

  • 发明设计人 MACOR JOHN E.;

    申请日1992-10-06

  • 分类号C07D209/16;A61K31/40;C07D401/12;C07D403/06;C07D403/12;C07D413/12;C07D417/12;C07D473/34;

  • 国家 CZ

  • 入库时间 2022-08-22 04:20:08

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