New n-heterocyclic propylidene-1,1-bis:phosphonic acids - useful as drugs influencing calcium metabolism for treating arthritic disorders, atherosclerosis etc.

摘要

N-Heterocyclic propylidene-1,1-bisphoric acids of formula (I) and their salts are new. R1 to R8 = H, or 1-10C aliphatic hydrocarbon; opt. R3 when taken together with R1 or R5 forms a satd. aliphatic 5-7-membered ring opt. substd. with one or more 1-4C alkyl. R1 to R8 = H or 1-4C alkyl. The salt is selected from alkali metal salt, alkaline earth metal and salts with ammonia or non-toxic amines.