Substituted imidazo 1,5-a pyridine derivatives and their 7,8-dihydro and 5,6,7,8-tetrahydro derivatives as well as 5H-5- (4-cyanophenyl) -6,7-dihydro-pyrrolo 1,2-c imidazole derivatives and salts thereof, a process for their preparation, their use for the manufacture of pharmaceutical compositions and to pharmaceutical compositions containing them

摘要

Compounds of the formula IMAGE (Ia) wherein R1 represents cyano, nitro or C1-C4-alkyl or the 7,8-dihydro derivative thereof or the 5,6,7,8 tetrahydro derivative of the formula IMAGE (Ib) wherein R1 is as defined under formula Ia and R2 is hydrogen, C1-C4-alkyl, halogen etherified or esterified hydroxy or mercapto, carboxy-C1-C4-alkyl or C1-C4-alkoxycarbonyl-C1-C4-alkyl or C1-C4-alkanoyl, to stereoisomers, mixtures of these stereoisomers and salts of these compounds are disclosed as well as their preparation, pharmaceutical compositions containing the same and the use thereof as inhibitors of aromatase activity.