The invention relates to a tissue adhesive in lyophilised form, which, besides fibrinogen and factor XIII and, where appropriate, other proteins and auxiliaries or additives, contains at least one biologically tolerated surfactant. It has been found that the presence of these biologically tolerated surfactants shortens the reconstitution time of lyophilised tissue adhesive compositions without adversely affecting the biochemical, mechanical or biological properties of the composition or the fibrin produced therefrom.
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