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Use of a human rhinovirus receptor preparation for the manufacture of medicaments for the treatment of rhinovirus infections
Use of a human rhinovirus receptor preparation for the manufacture of medicaments for the treatment of rhinovirus infections
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机译:人鼻病毒受体制剂在制备用于治疗鼻病毒感染的药物中的用途
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摘要
A water soluble human rhinovirus (HRV) major receptor preparation comprising detergent-complexed glycoprotein isolated from animal cells, preferably mammalian cells, that express the HRV major receptor and which exhibits the ability to bind to HRV capsids to substantially reduce infectivity of the virus. The purified, water soluble receptor is obtained by extracting cells expressing the receptor with detergent and isolating the solubilized detergent-glycoprotein complexes by binding to monoclonal antibody selective for the HRV receptor protein.
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