SUBSTANTIALLY PURE 2-METHYL-4-CARBOXY-3,4,5,6-TETRAHYDROPYRIMIDINE AND/OR THE 5-HYDROXY DERIVATIVE; ANALOGUES, PHARMACEUTICAL COMPOSITIONS, AND ISOLATION THEREOF FROM STREPTOMYCES CULTURE

摘要

The present invention relates to purified tetrahydropyrimidine derivatives and to pharmaceutical compositions comprising them. The tetrahydropyrimidine derivatives are useful for DNA protection from damaging by DNA-binding drugs, chemical carcinogens and mutagens and from irradiation.