TREATMENT OF MYELOSUPPRESSION ASSOCIATED WITH ACQUIRED IMMUNE DEFICIENCY.

摘要

PHARMACEUTICAL COMPOSITION AND METHODS OF TREATMENT ARE USEFUL FOR TREATING MYELOSUPPRESSION AND VIRAL INFECTIONS ASSOCIATED WITH AIDS, PARTICULARLY CYTOMEGALOVIRUS RETINITIS. SUCH COMPOSITIONS AND TREATMENTS UTILIZE AN ANTIVIRAL EFFECTIVE AMOUNT OF 9-(1,3-DIHYDROXY-2-PROPOXYMETHYL) GUANINE (DHPG) IN COMBINATION WITH AN ANTI-MYELOSUPPRESSIVE EFFECTIVE AMOUNT OF GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR (GM-CSF). THE USE OF DHPG AND OF GM-CSF FOR THE PREPARATION OF A PHARMACEUTICAL COMPOSITION FOR USE IN THIS COMBINATION TREATMENT AS WELL AS KITS CONTAINING PHARMACEUTICAL COMPOSITIONS CONTAINING DHPG AND GM-CSF ARE ALSO DISCLOSED.