A receptor protein specific human interferon gamma, antibody against said protein, methods for obtaining said protein and said antibody and said protein containing compositions and antibody.

摘要

ANALYSIS [125 I] GAMMA RETICULATED interferon to its receptor in various human cells by SDS-PAGE, revealed that there are at least three different types of human interferon GAMMA RECEPTORS. IN WISH, HeLa, FS11 AND OTHER TISSUE CELLS FOUND RECEIVER 90000-105000 MR. AND THE monocyte cell line KG-1 Myeloid FOUND MR RECEIVER 140.000, while the Daudi lymphoblastoid cell FOUND RECEIVER 95000-115000 MR. The various receptors were isolated from these cells, extracting and subjecting the extract to affinity chromatography on a column of GAMA Interferon IMMOBILIZED. Purified PREPARATIONS RESULTING retained their ORIGINAL AFFINITY Interferon GAMA and used to immunize MICE AND FOR THE SUBSEQUENT DEVELOPMENT OF ANTIBODY highly specific.