Progesterone-antagonistic and anti-oestrogen compounds for the therapy of leiomyomata uteri

摘要

At least one compound with a progesterone-antagonistic (PA) activity and at least one compound with an anti-oestrogen (AO) activity are used to prepare medicaments for the therapy of leiomyomata uteri (myoma of the uterus). When PA and AO are used in combination, the stimulation of the epithelium in the endometrium caused when only a progesterone-antagonistic compound is used is largely inhibited by the compound with anti-oestrogen activity.