TREATMENT OF RHEUMATOID ARTHRITIS WITH THALIDOMIDE ALONE OR IN COMBINATION WITH OTHER ANTI-INFLAMMATORY AGENTS

摘要

The present invention relates to a novel method for treating rheumatoid arthritis with thalidomide alone or in combination with anti-rheumatoid agents and/or with steroidal and/or non-steroidal anti-inflammatory drugs. The present invention also relates to methods of treating rheumatoid arthritis with tumor necrosis factor inhibitors as well as pharmaceutical compositions containing tumor necrosis factor inhibitors and steroidal and/or non-steroidal anti-inflammatory and/or anti-rheumatoid drugs. A further aspect of this invention relates to a special pharmaceutical composition containing thalidomide wherein said thalidomide has been micronized to a particle size of less than 1.0 microns. Compositions containing such micronized thalidomide exhibit faster absorption rates than previously known thalidomide formulations.