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Vaccines of which the characteristic epitope is incorporated in a picorna virus protein, particularly in that of the polio virus
Vaccines of which the characteristic epitope is incorporated in a picorna virus protein, particularly in that of the polio virus
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机译:特有的抗原决定簇结合在小核糖核酸病毒蛋白中的疫苗,尤其是在脊髓灰质炎病毒中
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摘要
The invention relates to an active principle of a vaccine whose characteristic epitope is incorporated in the capsid of a picoravirus, in particular, the poliovirus, which serves as the vector. This active principle consists of a viable picornavirus hybrid containing an epitope which is characteristic of a vaccinating protein and is heterologous in respect of the proteins of said picornavirus, instead of one of its own immunogenic epitopes.
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