Use of azole derivatives for the preparation of drugs useful for inhibiting the aromatase and treating of estrogen-dependent diseases

摘要

This invention provides a method of inhibiting aromatase and treating of estrogen-dependent diseases in a patient by administering azole derivatives as nonsteroidal inhibitors. The azole derivative has the formula CHEM where R1 is a hydrogen or a (c1-c5) alkyl;R2 is a hydrogen or a (c1-c5) alkyl;R3 is any of a halogen,a (c1-c5) alkyl, a halo(C1-C5)alkyl, a phenyl, a cyano or a nitro ; n is 0 to 5 ; and Y is a nitrogen atom or CH.