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Development of a mechanism-based screen to identify androgen receptor agonists and antagonists
Development of a mechanism-based screen to identify androgen receptor agonists and antagonists
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机译:基于机制的筛选方法的鉴定,以鉴定雄激素受体激动剂和拮抗剂
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摘要
The present invention relates to a novel androgen receptor screening method using a yeast-based expression system. The use of this yeast system enhances the ability to screen for agonists and/or antagonists of the steroid thyroid receptor superfamily. Furthermore, the use of this yeast system allows the localization and identification of functional domains of the androgen receptor.
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