Method for Separating and Purifying Cephalantine and Alkaloid Containing it from Stephanie Subspecies

摘要

The present invention relates to an improved method for separating and purifying sepharantine, an effective physiologically active substance, from an alimentary plant of Stephania and an alkaloid containing the same, wherein the dried lower alcohole extract of Stephania sepharta is dried under reduced pressure in a 2% hydrochloric acid solution After dissolving, the obtained filtrate is alkalized with an alkaline solution at pH 7-9, and then extracted with an extraction solvent selected from petroleum ether, cyclohexane and hexane to obtain an alkaloid dry matter containing sebalantine, /RTI ;The method of the present invention obtains the target with a high yield, which is increased by 50% or more as compared with the conventional method.