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Microorganisms producing 2-keto-L-gulonic acid and method for producing 2-keto-L-gulonic acid using the same
Microorganisms producing 2-keto-L-gulonic acid and method for producing 2-keto-L-gulonic acid using the same
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机译:生产2-酮-L-古洛糖酸的微生物和使用该微生物生产2-酮-L-古洛糖酸的方法
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摘要
The present invention relates to a microorganism producing 2-keto-L-gulonic acid and a process for producing 2-keto-L-gulonic acid using the same.;The present invention relates to a novel microorganism belonging to the genus Corynebacterium which has the ability to produce 2-keto-L-gulonic acid of the microorganism of the present invention and does not utilize 5-keto-D-gluconic acid as a carbon source. 5-keto-D-gluconic acid or L-idonic acid is cultured under aerobic conditions in a culture medium of Corynebacterium sp. To obtain 5-keto-D-gluconic acid or L-Keto-L-gulonic acid, accumulating 2-keto-L-gulonic acid in the culture medium, and recovering 2-keto-L-gulonic acid from the culture medium.;According to the method of the present invention, 2-keto-L-gulonic acid used as an intermediate raw material of vitamin C can be efficiently produced, and 2-keto-L-gulonic acid is converted to vitamin C through methylation and lactonization.
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