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Derivatives of the n - quinoline, their process of preparation, # # obtained, their application as medicinal products and the compositions containing them.

机译:正喹啉的衍生物,其制备方法,获得的#号,作为医药产品的用途以及包含它们的组合物。

摘要

The invention relates to the products: IMAGE in which: R1 represents hydrogen, alkyl, alkenyl or alkynyl or acyl, cyano or free, salified or esterified carboxyl, R2 and R3, which are identical or different, represent in particular: a) hydrogen, b) alkyl, alkenyl, alkynyl, alkyloxy or alkylthio, c) aryl, arylalkyl, arylalkenyl, aryloxy or arylthio, R5 represents a divalent alkylene, Y represents -Y1-B-Y2 in which: Y1 and Y2 represent in particular an optionally substituted aryl radical, B represents in particular a single bond between Y1 and Y2, and to the addition salts of the said products of formula (I). These products have advantageous pharmacological properties which justify their use as medicaments.
机译:本发明涉及以下产品:<图像>其中:R1代表氢,烷基,烯基或炔基或酰基,氰基或游离的,成盐或酯化的羧基,R2和R3相同或不同,尤其表示:a)氢; b)烷基,烯基,炔基,烷氧基或烷硫基,c)芳基,芳基烷基,芳基烯基,芳氧基或芳硫基,R5代表二价亚烷基,Y代表-Y1-B-Y2,其中:Y1和Y2特别代表在任选取代的芳基上,B特别代表Y 1和Y 2与所述式(I)产物的加成盐之间的单键。这些产品具有有利的药理性质,证明其可作为药物使用。

著录项

  • 公开/公告号FR2680511B1

    专利类型

  • 公开/公告日1995-05-19

    原文格式PDF

  • 申请/专利权人 ROUSSEL UCLAF;

    申请/专利号FR19910010433

  • 申请日1991-08-20

  • 分类号C07D215/233;A61K31/395;C07C69/618;C07D237/26;C07D401/06;

  • 国家 FR

  • 入库时间 2022-08-22 04:07:14

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