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Methods for the detection of BCR-ABL and abnormal ABL proteins in leukemia patients
Methods for the detection of BCR-ABL and abnormal ABL proteins in leukemia patients
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机译:白血病患者BCR-ABL及异常ABL蛋白的检测方法
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摘要
The present invention provides methods for detecting and quantitating BCR-ABL gene products and other abnormal ABL gene products of Ph.sup.1 - positive leukemic cells. The invention further provides methods for determining the relative number of leukemic cells compared with normal ABL cells to assess the tumor burden of a patient. In another aspect, the methods of the present invention can be used to determine a specific phase of leukemia, particularly chronic-phase CML.
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