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ANTIPARBOVIRUS INFECTIOUS DISEASE COMPOSITION

机译:猪破伤风病毒感染疾病组成

摘要

PURPOSE: To obtain the subject composition containing an antibody obtained from an egg yolk of a hen immunized with dog parbovirus and exhibiting preventive effect extremely effective against a parbovirus infectious disease of a young dog or cat in the period at which vaccine can not effectively be affected. ;CONSTITUTION: This composition contains an antibody obtained from an egg yolk of a hen immunized with a dog parbovirus. An antigen virus is inoculated to egg-laying hen exceeding 200 day age in an viral amount of 103 to 108 TCID50 (TCID50 is 50% infected amount in a cultured cell) per hen by subcutaneous injection or intramuscular injection. High antibody value is preferably obtained by carrying out additional immunity after 3 to 4 weeks from the first time immunity. An extracting method by chloroform, etc., or precipitation method, etc., for using polyethylene glycol is generally exemplified as a method for recovering an antibody from egg yolk. Furthermore, symptom of vomition or diarrhea accompanied by parbovirus infectious diseases is preferably improved by simultaneously blending the composition with sugar and electrolyte. Further, vitamins are preferably added thereto.;COPYRIGHT: (C)1996,JPO
机译:目的:获得包含从用狗细小病毒免疫的母鸡的蛋黄获得的抗体的主题组合物,该抗体在不能有效影响疫苗的时期内表现出对幼犬或猫的细小病毒感染性疾病极为有效的预防作用。 ;组成:该组合物包含一种抗体,该抗体是从用狗细小病毒免疫的母鸡的蛋黄中获得的。将抗原病毒以10 3 至10 8 TCID 50 (TCID < Sub> 50 是每只母鸡通过皮下注射或肌内注射感染的50%的感染细胞。高抗体值优选通过从第一次免疫起3-4周后进行额外的免疫而获得。作为从蛋黄中回收抗体的方法,通常例示了使用聚乙二醇的氯仿等的提取方法或沉淀法等。此外,优选通过同时将组合物与糖和电解质混合来改善伴随小肠病毒感染性疾病的呕吐或腹泻症状。此外,优选向其中添加维生素。;版权所有:(C)1996,JPO

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