TRANSGENIC RABBITS WHICH EXPRESS HUMAN ERYTHROPOIETIN (EPOH) IN THE MILK OF THE FEMALES

摘要

The present Invention relates to the fields of Genetic Engineering and BiotechnologyAnd more specifically with the transgenic animals.This Invention aims to obtain a line of Rabbits capable of producing Foreign Protein (Epoh) in the Milk of their females.Its Essence is that the Genome of a line of Rabbits has been modified through the introduction of a segment of desoxirr acidIbonucleico (DNA) that contains the information necessary for the synthesis and secretion of Human Milk Protein.The animals were obtained by Crossing homozygous for the new character,With which we obtained a stable line of Transgenic Rabbits.This line of transgenic animals could be very useful in studies aimed at Deciphering the mechanisms of Protein SecretionThe Milk of mammalsAs well as certain amounts of Human Protein is properly formed and active paRa Analytical tests, their Therapeutic use and CommercialAs for Studies on the functioning of the various control elements that integrate the Transgene in different tissues and during LAs different stages of the Life of the animal. !