首页> 外国专利> N-££4-£4-(4-FLUOROPHENOXY)BUTY/ -4- PIPERIDY/ -N- METHYLAMINO -2-BENZOTHIAZOLOLES, PROCESS OF THEIR PREPARATION, ANTI-ARRHYTHMIC PREPARATIONS BASED THEREON AND PROCESS FOR PREPARING THEREOF

N-££4-£4-(4-FLUOROPHENOXY)BUTY/ -4- PIPERIDY/ -N- METHYLAMINO -2-BENZOTHIAZOLOLES, PROCESS OF THEIR PREPARATION, ANTI-ARRHYTHMIC PREPARATIONS BASED THEREON AND PROCESS FOR PREPARING THEREOF

机译:N-££4-£4-(4-氟苯氧基)BUTY / | -4- PIPERIDY / | -N-甲基氨基| -2-苯并噻唑,其制备方法,基于其的抗心律失常制备及其制备方法

摘要

the solution relates to the 2 - | | | 1 - 4 - (4-fluorophenoxy) butyl | - 4-piperidyl | methilamino | benzothiazololu016f of general formula i, where one of the symbols r.sup.1.n. and r.sup.2.n.a hydroxyskupinu, while the second represents a hydrogen atom, and their pharmaceutically suitable addition salts with acids, and their use as anti arrhythmic medicinal products of class iii and method of their production.in this way, with an intermediate formula ii where r.sup.1.n. and r.sup.2.n. have the above meaning n - alkyluje reagent of general formula (iii), where w represents the reactive outgoing group.the solution also includes anti arrhythmic pharmaceutical devices based on these compounds and method for their production. and
机译:解决方案涉及2-| | | 1-4(4-氟苯氧基)丁基| -4-哌啶基| methilamino |通式I的苯并噻唑醇,其中符号r.sup.1.n之一。和r.sup.2.na hydroxyskupinu,第二个代表氢原子,以及它们与酸的药学上合适的加成盐,以及它们作为iii类抗心律不齐药物的用途及其生产方法。中间式ii其中r.sup.1.n。和r.sup.2.n.具有上述含义的通式(iii)的n-烷基试剂,其中w表示反应性离去基团。溶液还包括基于这些化合物的抗心律不齐药物装置及其制备方法。 r和

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