首页> 外国专利> An oxazolidinedione derivative, its production and a pharmaceutical composition for lowering blood sugar and lipid in blood comprising the same

An oxazolidinedione derivative, its production and a pharmaceutical composition for lowering blood sugar and lipid in blood comprising the same

机译:恶唑烷二酮衍生物,其制备物和用于降低血液中血糖和脂质的药物组合物

摘要

2,4-Oxazolidinedione derivative represented by the formula: CHEM wherein R stands for an optionally substituted hydrocarbon residue or heterocyclic group; Y stands for a group represented by -CO-, -CH(OH)- or -NR3- (wherein R3 stands for an optionally substituted alkyl group); m is 0 or 1; n is 0, 1 or 2; A stands for a C1-7 divalent aliphatic hydrocarbon group; R1 stands for hydrogen or an alkyl group; ring E stands for a benzene ring having 1 or 2 substituents; L and M respectively stand for hydrogen, or L and M may optionally be combined with each other to form a bond; with a proviso that the partial formula: CHEM does not include the formula: CHEM wherein R' stands for an alkyl group; or a salt thereof, which has excellent actions of lowering blood sugar and lipid in blood.
机译:由下式表示的2,4-恶唑烷二酮衍生物:其中R代表任选取代的烃基或杂环基。 Y代表-CO-,-CH(OH)-或-NR 3-表示的基团(其中R 3代表任选取代的烷基); m为0或1; n为0、1或2; A代表C1-7二价脂族烃基; R 1表示氢或烷基。 E环代表具有1或2个取代基的苯环; L和M分别代表氢,或者L和M可以任选地彼此结合形成键;条件是部分式:不包括式:其中R'代表烷基;或其盐,具有降低血液中血糖和脂质的优异作用。

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