Active compound in the serotonin 5-ht receptor useful in the treatment of Diseases of the CNS.

摘要

Refers to a compound of formula I: where R1 and R7 are each Halo, triflurometilo alkyl of C1 - C6, among others; R2 and R3 are each Hydrogen or c1-c6 alkyl; R4 and R5 are each Hydrogen,Halo, trifluoromethyl, among others; R4 is Hydrogen, alkyl phenyl optionally substituted C1 - C6, among others, M and P are each from zero to four,Preferably M is zero to two; n is one to four, is preferably one or two; Z is N - R9, - O -, - S - among others, preferably the first; where R9 is H,Among other C1 - C6 alkyl; X is Oxygen or sulfur, oxygen and is Preferred; n - (C - - n or - r11r12 cr11r12 R11 and R12 are; where each h, alkyl of C1 - C6, trifluoromethyl, among others.This Compound is used in the treatment of Central Nervous System Diseases