OPTICALLY ACTIVE RHODIUM COMPLEXES OF 3,4-BIS(DIARYLPHOSPHINO)PYRROLIDINES AND THEIR USE FOR THE PREPARATION OF PHOSPHINOTHRICIN BY ASYMMETRIC HYDROGENATION

摘要

The invention relates to rhodium complexes of the formula[A - 0 - (CH2CH20)n - A]2+ 2 X- Iaand[A - 0 - (CH2CH20)m - CH3]+ X- Ibin whichn = 5-1,000,m = 5- 250,X denotes a tetrafluoroborate, hexafluorophosphate orper-chlorate anion,A denotes a radical of the formula II(en)2 denotes two molecules of a monoolefin or one mole-cule of a diolefinAr denotes phenyl or phenyl which is substituted by oneor two alkyl groups having 1 or 2 carbon atoms andR1 denotes an arylene or alkylene bridge, and their usefor the preparation of L-phosphinothricin and itsderivatives by enantioselective catalytic hydrogenationof 2,3-dehydrophosphinothricin (derivatives).