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NUCLEIC ACIDS OF ROCHALIMAEA HENSELAE AND ROCHALIMAEA QUINTANA AND METHODS AND COMPOSITIONS FOR DIAGNOSING ROCHALIMAEA HENSELAE AND ROCHALIMAEA QUINTANA INFECTION
NUCLEIC ACIDS OF ROCHALIMAEA HENSELAE AND ROCHALIMAEA QUINTANA AND METHODS AND COMPOSITIONS FOR DIAGNOSING ROCHALIMAEA HENSELAE AND ROCHALIMAEA QUINTANA INFECTION
A method of diagnosing cat scratch disease and a method of diagnosing bacillary angiomatosis in a subject by detecting the presence of Rochalimaea henselae or an antigenic fragment thereof in the subject is provided. Also provided is a vaccine comprising an immunogenic amount of a nonpathogenic Rochalimaea henselae or an immunogenically specific determinant thereof and a pharmaceutically acceptable carrier. A method of diagnosing Rochalimaea quintana infection in a subject by detecting the presence of a nucleic acid specific to Rochalimaea quintana in a sample from the subject is provided. A purified, 60-kDa heat shock protein of Rochalimaea is provided. Also provided is a 17-kDa antigenic polypeptide of Rochalimaea.
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