SOLUTIONS OF ARYL OR HETEROARYL SUBSTITUTED ALKANOIC ACIDS IN LIPOPHILIC SOLVENTS AND SOFT GELATIN CAPSULES CONTAINING SUCH SOLUTIONS

摘要

Methods and compositions are disclosed for preparing liquid mixtures of aryl or heteroaryl alkanoic acids suitable for encapsulation in soft gelatin capsules. The compositions comprise alkanoic acids of formulas (I), (Ia), (Ib) or pharmaceutically acceptable salts thereof, wherein R, R1, R2, R3, and R5 represent hydrogen or various organic substituents, and an effective solubilizing amount of at least one lipophilic solvent.