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SYNTHETIC PEPTIDES OF M. GALLISEPTICUM, ANTIBODIES THERETO, THEIR PREPARATION AND USE

机译:M.Gallisepticum的合成肽,其抗体及其制备和使用

摘要

The invention describes novel synthetic peptides imitating natural epitopes on the membrane of pathogenic mycoplasma M. gallisepticum and a process for the preparation thereof. By the mentioned peptides native antigens in serological tests can be substituted and they can be used as vaccines or as antigens for the preparation of antibodies. Antibodies prepared by means of these peptides recognize native mycoplasma epitopes and are useful in various diagnostic tests for determination of poultry infections with M. gallisepticum, they prevent the growth of the mentioned mycoplasma and are also suitable for the isolation of native or recombinant main immunogenic protein pMGA or its subunits.
机译:本发明描述了模仿病原性支原体支原体支原体膜上的天然表位的新型合成肽及其制备方法。通过提及的肽,血清学测试中的天然抗原可以被取代,它们可以用作疫苗或制备抗体的抗原。通过这些肽制备的抗体可识别天然支原体表位,可用于各种诊断测试以确定鸡败血支原体的家禽感染,它们可防止上述支原体生长,也适用于分离天然或重组主要免疫原性蛋白pMGA或其亚基。

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