RETROVIRAL VECTORS CAPABLE OF EXPRESSING MULTIMERIC PROTEINS FROM MULTIPLE TRANSLATIONAL INITIATION SITES

摘要

This invention relates to retroviral vectors that express multiple polypeptide subunits of a eukaryotic protein from a single polycistronic mRNA and the proteins produced from these vectors. The expressed proteins are particularly useful for inducing transplantation tolerance and the vectors are useful as agents for mediating gene transfer into eukaryotic cells.