Novel, racemic 1-(substd.-amino-methyl) -octa-hydro-indole-(2,3-a)-quinolizine derivs. (i) and their pharmaceutically useful acid adduct salts are prepd. from 1-(substd.-sulphonyl-oxy-methyl)-octa-hydro-indolo(2,3-a)-quinoli- zine derivs. (ii) and a prim. amine of formula R2-NH2. (iii) R2 in (1) and (iii) = 1-6C alkyl, 4-8C cycloalkyl or opt. substd. aryl and aralkyl or an aralkyl gp. opt. contg. heteroatom. R1 = 1-6C substd. alkyl or aryl gp. The reaction takes place in an inert organic solvent at its opt. acid adduct salts are pred. The prepns. have a gasto-cytoprotective effect.
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