首页> 外国专利> Novel fused indan derivatives and their pharmaceutically acceptable salts (NOVEL FUSED INDEN DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF)

Novel fused indan derivatives and their pharmaceutically acceptable salts (NOVEL FUSED INDEN DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF)

机译:新型稠合茚满衍生物及其药学上可接受的盐(新型稠合茚满衍生物和药学上可接受的盐)

摘要

A condensed-indan derivative of the general formula (I) and pharmaceutically acceptable salts thereof:;Wherein ring A is an optionally substituted benzene ring or naphthalene ring or a benzene ring having a lower alkylenedioxy group and ring B is an optionally substituted benzene ring or a benzene ring having a lower alkylenedioxy group, N = CR-or-CR = N-, and R is-NROneR2Group, an optionally substituted nitrogen-containing heterocyclic group, or-OR3Group, ROneAnd R2Are the same or different and each is a hydrogen atom; Phenyl group; An optionally substituted nitrogen-containing heterocyclic group; Or an optionally substituted amino group, a lower alkoxy group, a phenyl group, a nitrogen-containing heterocyclic group, an amine oxide group substituted by a lower alkyl group, or a hydroxyl group (s) Lower alkyl group, R3Is a lower alkyl group optionally substituted by a substituted amino group, provided that when R is an optionally substituted nitrogen-containing heterocyclic group, ring A and ring B are not a benzene ring without substituent.
机译:通式(I)的缩合茚满衍生物及其药学上可接受的盐:其中环A为任选取代的苯环或萘环或具有低级亚烷基二氧基的苯环,环B为任选取代的苯环或具有低级亚烷基二氧基的苯环,N = CR-或-CR = N-,且R为-NR One R 2 基团,可任选取代的含氮原子杂环基或-OR 3 基,R One 和R 2 相同或不同,各自为氢原子;苯基;任选取代的含氮杂环基;或任选取代的氨基,低级烷氧基,苯基,含氮杂环基,被低级烷基取代的氧化胺基或羟基低级烷基,R Sub 3 是任选地被取代的氨基取代的低级烷基,条件是当R是任选取代的含氮杂环基时,环A和环B不是没有取代基的苯环。

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