METHOD FOR PRODUCTION OF ARYL PIPERAZINE HETEROCYCLIC COMPOUNDS OR THEIR PHARMACEUTICALLY ACCEPTABLE ACID ADDITIVE SALT

摘要

FIELD: organic chemistry. SUBSTANCE: piperazine having formulae (2) is used as reagent 1, alkyl halide-containing compound having formula (3) is used as reagent 3. Reaction is carried out by heating to boiling point, reaction takes place in water in the presence of sodium carbonate, its quantity being 1-4 molar equivalents as calculated for origin reagent. Desired product which has formula (1) is prepared at yield 88-91 %. Said product has neuroleptic activity. EFFECT: improves quality of desired product.