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MONOMERIC ANTIBODY, METHOD OF ANTIBODY PREPARING, DIMERIC FUSED PROTEIN, METHOD OF PROTEIN PREPARING, SET OF STRUCTURES
MONOMERIC ANTIBODY, METHOD OF ANTIBODY PREPARING, DIMERIC FUSED PROTEIN, METHOD OF PROTEIN PREPARING, SET OF STRUCTURES
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机译:单体抗体,抗体制备方法,二元融合蛋白,蛋白制备方法,结构集
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摘要
FIELD: biotechnology, immunochemistry. SUBSTANCE: invention describes the new class of molecules binding antigens that contains Fv-fragments of antibody but does not use the constant regions of antibody. They can dimerize also with molecule fragments of other antibodies or with molecule fragments of non-antibodies with formation of bi- or multifunctional fused proteins of antibody fragment and so called mini-antibodies, respectively. New fused proteins can be used for diagnosis and in therapeutical medicine. EFFECT: improved method of antibody and protein preparing.
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