Method of determining blood coagulation factor XIII activity and kit of reagents for the determination

摘要

An accurate, rapid and simple method of determining blood coagulation factor XIII activity and a kit of reagents therefor are provided. A sample and a fibrin precipitation inhibitor are mixed, or a sample, fibrinogen and a fibrin precipitation inhibitor are mixed; a thrombin solution is added; the fibrin coagulation time is measured in the presence of calcium ion; and the coagulation time is compared with the normal coagulation time. The kit for the determination comprises thrombin, calcium ion and a fibrin precipitation inhibitor, and may be combined with fibrinogen.