Host cell line LVIP2.0Zc, useful in assays to identify ligands and ant agonists of G protein-coupled receptors

摘要

The present invention relates, in general, to a method of identifying ligands and antagonists of ligands. In particular, the present invention relates to a method of identifying ligands and antagonists of ligands which bind to cloned G.sub.s - or G.sub.i -coupled receptors. The present invention also relates to a cell that comprises a recombinant cyclic AMP sensitive reporter construct.