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Adenovirus vectors for hemophilia treatment
Adenovirus vectors for hemophilia treatment
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机译:用于血友病治疗的腺病毒载体
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摘要
An adenoviral vector including at least one DNA sequence encoding a clotting factor, such as, for example, Factor VIII, or Factor IX. Such vectors may be administered to a host in an amount effective to treat hemophilia in the host. The vectors infect hepatocytes very efficiently, whereby the hepatocytes express the DNA sequence encoding the clotting factor.
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