The region unique recombinase/the adjustment of the region unique rearrangement by the nuclear reseputa fusion protein

摘要

(57) Abstract It states the cell, the living thing or concerning this invention which makes the adjustment of rearrangement inside suitable cell-free system possible. This invention, the component of the recombinase protein or recombinase type, with includes the fact that create the fusion protein with the ligand join Characteristic domain which was induced from nuclear reseputa. This fusion protein, during non existing of the ligand which is joined to ligand join Characteristic domain, just barely shows recombinase activity. Recombinase activity is induced during join of the ligand. This invention offers the execution means in order to adjust rearrangement inside the cell and the living thing, when rearrangement is achieved and ligand join by linking doing in rearrangement, ligand join, offers the simple kind of means which can be measured with that.