Provides a procedure for preparing hydrochloride (1 - 2 - Deoxy - 2.2 - difluoro - D - ribofuranosil) - 4 - aminopiridin - 2 - One clorhidratode gemcitabine of formula (i),Separating the benzoyl groups blocking compounds debeta - 1 - (2 - Deoxy - 2.2 - difluoro - 35 - Di - or - Benzoyl - D - ribofuranosil) - 4 - aminopirimidina - 2 - one in the presence of catalytic amounts of alkylamines in methanol or ethanol Solvent, under exclusion of water.Gemcitabine hydrochloride was formed recuperatratando solution with hydrochloric acid and unantisolvente.
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