首页> 外国专利> Oral pharmaceutical form of multiple unit dosage in tablet processes for preparation of the same for inhibition of gastric acid secretion in mammals and man and for the treatment of diabetesThe inflammatory disorders in mammals and man and packaging of separating pressure transverse

Oral pharmaceutical form of multiple unit dosage in tablet processes for preparation of the same for inhibition of gastric acid secretion in mammals and man and for the treatment of diabetesThe inflammatory disorders in mammals and man and packaging of separating pressure transverse

机译:片剂工艺中多单位剂量的口服药物形式,用于制备该制剂以抑制哺乳动物和人的胃酸分泌以及治疗糖尿病哺乳动物和人的炎症性疾病以及横向分压包装

摘要

An oral pharmaceutical multiple unit tabletted dosage form comprises tablet excipients and individually enteric-coated layered units of a core material contg. omeprazole (5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl) sulphinyl)-1H-benzimidazole) or 1 of its alkaline salts, or a single enantiomer, opt. mixed with alkaline cpds., covered with 1 or more layers, at least 1 being an enteric coating layer. The mechanical properties of the enteric coating layer ensure that acid resistance of the individual coated units is not significantly affected when they are compressed with excipients into tablets.
机译:口服药物多单位压片剂型包含片剂赋形剂和核心材料含量的单独肠溶衣分层单位。奥美拉唑(5-甲氧基-2-((((4-甲氧基-3,5-二甲基-2-吡啶基)甲基)亚磺酰基)-1H-苯并咪唑)或其碱性盐之一,或单一对映异构体。与碱性cpds混合,覆盖一层或多层,至少一层为肠溶衣层。肠溶衣层的机械性能确保了各个包衣单元在与赋形剂一起压制成片剂时不会显着影响其耐酸性。

著录项

  • 公开/公告号BR9506018A

    专利类型

  • 公开/公告日1997-09-02

    原文格式PDF

  • 申请/专利权人 ASTRA AKTIEBOLAG;

    申请/专利号BR19959506018

  • 申请日1995-06-07

  • 分类号A61K9/26;A61K9/20;A61K31/44;

  • 国家 BR

  • 入库时间 2022-08-22 03:27:44

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