Components of saponia process for isolation of saponin vaccine formulation and process for increasing antigenicity of an antigen in a vaccine formulation

摘要

PCT No. PCT/KR96/00053 Sec. 371 Date Dec. 6, 1996 Sec. 102(e) Date Dec. 6, 1996 PCT Filed Apr. 12, 1996 PCT Pub. No. WO96/32401 PCT Pub. Date Oct. 17, 1996A novel saponin component having a molecular weight of about 956 daltons, a process for isolating the saponin component from the bark of Quillaja saponaria Molina, a vaccine formulation comprising the saponin component as an immune adjuvant, a method for increasing the immune response to an antigen by employing an adjuvant composition comprising saponin component and a second adjuvant.