Monoclonal antibodies that inhibit the growth of Kaposi's sarcoma

摘要

The present invention involves the use of monoclonal antibodies specific for Oncostatin M to inhibit the growth potentiating effect of Oncostatin M on Kaposi's Sarcoma associated with AIDS. In particular neutralizing anti-Oncostatin M antibodies inhibit the growth of Kaposi's Sarcoma which is potentiated and maintained by Oncostatin M or a factor found in conditioned media of an HTLV-II transformed T cell line.