Heterosykliske forbindelser med tachykininreseptor-antagonistaktivitet, deres fremstilling og anvendelse

摘要

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to compounds of the formula (I) and their quaternary ammonium derivatives of the formula (Ia) (value see in p. 1 of the claim) and composition based on said that show antagonistic effect with respect to neurokinin-1 and neurokinin-2 and can be used for treatment and prophylaxis of central nervous system diseases, respiratory sicknesses, allergy. EFFECT: enhanced effectiveness of treatment and prophylaxis. 95 cl, 10 tbl, 87 ex