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with a simple unsaturated c18 or c20 fatty acid omega 9 o acylierte nukleoside
with a simple unsaturated c18 or c20 fatty acid omega 9 o acylierte nukleoside
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机译:具有简单的不饱和c18或c20脂肪酸ω9 o酰基核苷
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摘要
Fatty acid esters (I) of nucleosides or nucleoside analogues are new, where the fatty acid is a monounsatd. 18 to 20C fatty acid esterified with the 5'-OH gp. of nucleosides or with an OH gp. on the noncyclic chain of nucleoside analogues. (I) have higher activity than the parent nucleosides or analogues and have relatively low toxicity. Pref., (I) are esters of acyclovir, Ara T, Ara A or AZT with oleic acid, elaidic acid or cis- or trans-eicosenic acid.
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