STEROIDS WITH 2BETA, 19-ETHYLENE BRIDGES AS AROMATASE INHIBITORS.

摘要

THE CURRENT INVENTION IS AIMED AT A GROUP OF ANDROSTANE COMPOUNDS CONTAINING AN ETHYLENE RADICAL THAT LINKS POSITIONS 2 AND 29. THESE COMPOUNDS ARE USED AS INHIBITORS OF AROMATASES AND ARE PREPARED BY THE CYCLING OF A 19- (2- ( 4-TOLUENOSULFONYLOXYL) ETIL) ANDROST-4-ENO-3,17-DIONE USING A STRONG BASE