COMPOSITIONS COMPRISING AN HIV PROTEASE INHIBITOR SUCH AS VX478 AND A WATER SOLUBLE VITAMIN E COMPOUND SUCH AS VITAMIN E-TPGS

摘要

Pharmaceutical formulations containing HIV protease inhibitors, specifically including 3S-¢3R*(1R*,2S*)!-¢3-¢¢(4-aminophenyl)sulphonyl!(2-methylpropyl)-amino!-2-hydroxy-1-phenylmethyl)propyl!carbamic acid, tetrahydro-3-furanyl ester (alternatively known as VX 478 or 141W94), and a tocopherol, and their use in medical therapy are described.