INDUCTION OF E-SELECTIN FOR TARGETTING THERAPEUTICINDUCTION OF E-SELECTIN FOR TARGETTING THERAPEUTIC AGENTS AGENTS

摘要

Disclosed are a variety of compositions and methods for use in specifically targeting the L-selectin or preferably, the E-selectin marker following its cell surface induction, e.g., using ionizing radiation, in tumor vasculature endothelial cells. The compositions and methods described are suitable for use in the delivery of selected agents to tumor vasculature, as may be used in the diagnosis aid therapy of solid tumors.