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ISLET-SPECIFIC HOMEOPROTEIN AND TRANSCRIPTIONAL REGULATOR OF INSULIN GENE EXPRESSION
ISLET-SPECIFIC HOMEOPROTEIN AND TRANSCRIPTIONAL REGULATOR OF INSULIN GENE EXPRESSION
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机译:胰岛特定的胰岛素和转录调控因子在胰岛素基因表达中的作用
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摘要
The invention relates to a homeoprotein regulator of insulin gene expression having the characteristics of: binding to an element of an insulin gene promoter; being modulated by a Ca++-dependent CaM kinase IV; and having homology to a nucleotide sequence encoded by a Hox gene complex. Also included within the invention are DNA sequences encoding the homeoprotein regulators of insulin gene expression, antibodies directed to the homeoprotein regulators of insulin gene expression, and diagnostic and therapeutic materials and utilities for the homeoprotein regulators of insulin gene expression.
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